Dr. Brian Acacio, MD, FACOG

About

Dr. Brian Acacio is a reproductive endocrinologist — the specialty that manages hormone-driven fertility problems and IVF — and the founder of Acacio Fertility Center in Bakersfield, California. He is board-certified in Reproductive Endocrinology and Infertility (REI) by the American Board of Obstetrics and Gynecology and a Fellow of the American College of Obstetricians and Gynecologists (FACOG).

His clinical signature is reproductive immunology: figuring out why embryos fail to implant or why pregnancies end early when the obvious mechanical and hormonal causes don’t explain it. That niche has made him a referral point for other providers in Southern California handling stubborn repeat-implantation-failure and recurrent-loss cases.

He trained in medicine at George Washington University and completed both his OB/GYN residency and his REI fellowship at Los Angeles County-USC Medical Center.

Clinical Expertise

• Reproductive immunology: Immune-focused workup and targeted protocols for infertility with a suspected immunologic component — the through-line of his practice.
• Repeat implantation failure (RIF): Systematic evaluation of patients who have not conceived after multiple quality embryo transfers, with intervention aimed at implantation rather than just another cycle.
• Recurrent pregnancy loss (RPL): Cause-finding across immune, clotting, and chromosomal factors, followed by case-specific treatment.
• PCOS: Stimulation and IVF protocols tuned to balance egg yield against ovarian hyperstimulation risk.
• IVF & ICSI: Full-cycle management from stimulation through retrieval, fertilization, and transfer.
• Ovarian regeneration (PRF): Platelet-rich fibrin treatment for patients with diminished ovarian reserve.

Why Choose Dr. Brian Acacio

• A genuine subspecialty focus: Reproductive immunology is uncommon as a primary practice emphasis. Patients with unexplained implantation failure often cannot find that depth at a high-volume clinic.
• Peer recognition: Named a Super Doctor for multiple consecutive years; our source does not list the years. It is a peer-nominated distinction rather than a patient-voted one.
• Academic footing: UCLA clinical associate professor, and author of 50+ peer-reviewed papers and presentations.
• Continuity of care: As a single-attending practice, you see Dr. Acacio rather than being handed between physicians mid-cycle.

Professional Affiliations

• Fellow of the American College of Obstetricians and Gynecologists (FACOG)
• Member, American Society for Reproductive Medicine (ASRM)
• Member, Pacific Coast Reproductive Society (PCRS)
• Licensed to practice medicine in California

Suitable For

• Repeat implantation failure: If you have transferred good-quality embryos more than once without achieving a pregnancy, Dr. Acacio’s immunology-led workup targets causes a standard cycle review tends to miss.
• Suspected immune-related infertility or loss: Patients who want a full immune, clotting, and chromosomal evaluation behind unexplained infertility or early losses.
• PCOS: Anyone whose priority is a stimulation plan that protects egg response while managing OHSS risk.