'%20d='m0%200%2016%2011h61%2061%2061%2061%2060L47%2037h61%2061%2060%2061L16%2063h61%2061%2061%2061%2060L47%2089h61%2061%2060%2061L16%20115h61%2061%2061%2061%2060L47%20141h61%2061%2060%2061L16%20166h61%2061%2061%2061%2060L47%20192h61%2061%2060%2061L16%20218h61%2061%2061%2061%2060z'/%3e%3c/svg%3e)
About
Dr. Mamie McLean is a reproductive endocrinologist at Alabama Fertility specializing in infertility evaluation and treatment, IVF, third-party reproduction, and recurrent pregnancy loss. She built her practice around long-term relationships with patients and families, and on walking couples through the hardest decisions in fertility care — donor eggs, embryo number, when to change course — in plain language.
She grew up in Athens, Georgia, and trained entirely in the Southeast: University of Virginia for undergrad, Medical College of Georgia for medical school, UNC Chapel Hill for Ob/Gyn residency, and UAB for her REI fellowship.
That fellowship turned into three years of faculty at UAB, where she directed the university’s oocyte donor program — donor screening and medical and genetic evaluation, recipient matching, and donor cycle management. Very few community practice physicians have run an academic donor program end to end; it is the backbone of the donor egg services Alabama Fertility offers today, both its in-house fresh donor program and frozen eggs from Fairfax EggBank. She has won multiple teaching awards and was named a Top Woman in Medicine by B Metro in 2017.
Clinical Expertise
- IVF with individualized stimulation: protocols built around age, ovarian reserve, and prior response — with specific experience in diminished reserve and poor responders
- Egg donation, fresh and frozen: donor selection, matching, cycle synchronization, and the trade-offs between an in-house fresh program and banked frozen eggs, explained with direct program-management experience
- Recurrent pregnancy loss (RPL): systematic workup of karyotype, uterine anatomy, endocrine, and immune factors before treatment changes
- Third-party reproduction: donor egg and donor sperm pathways, including the medical and coordination side of legal agreements
- Fertility preservation: egg and embryo freezing counseling and execution
Why Choose Dr. McLean
Her three years directing UAB’s egg donor program mean a donor-egg patient is being seen by the person who built the matching pipeline, not just someone ordering from a catalog. She can lay out honestly when a fresh donor cycle is worth the coordination and when Fairfax EggBank’s tested, shippable frozen inventory is the faster, cheaper route.
For recurrent loss, her approach is a full differential: chromosome analysis, cavity assessment, and endocrine and immune workup, sequenced so you are not repeating tests you’ve already had. The same applies to low ovarian reserve — she adjusts the protocol to the patient’s numbers rather than running a standard dose and hoping.
Her teaching background shows up in appointments. She is known for making sure couples actually understand the decision tree they are on — a real difference when the next step involves donor gametes or a transfer number choice, and both partners need to be on the same page.
Professional Affiliations
Dr. McLean is board certified by the American Board of Obstetrics and Gynecology in Obstetrics and Gynecology and in Reproductive Endocrinology and Infertility, a Fellow of ACOG, and a member of the American Society for Reproductive Medicine (ASRM). She trained at UVA, the Medical College of Georgia, UNC Chapel Hill, and UAB, where she later served on faculty.
Suitable For
Donor egg patients — fresh or frozen, single-center or bank-sourced. Dr. McLean ran an academic donor program for three years and handles the medical matching, screening review, and cycle logistics personally.
Recurrent pregnancy loss — couples who have had two or more losses and want a structured workup (genetic, anatomic, endocrine, immune) before another attempt.
Diminished ovarian reserve and advanced maternal age — low AMH, few antral follicles, or prior poor response. She plans mild or modified stimulation around your actual numbers instead of defaulting to a high-dose protocol.
LGBTQ+ families and single parents by choice — donor sperm and donor egg paths for female couples and solo parents, managed within a practice that routinely handles third-party reproduction.