Mitchell Scott Rein, MD

About

Mitchell Scott Rein spent nineteen years as chief medical officer and senior vice president at Salem Hospital, from 2004 through 2023, after serving as its chair of obstetrics and gynecology from 1997 to 2006. That is two decades of responsibility for whether a hospital’s surgical and obstetric services run safely — complication review, credentialing, infection rates, the unglamorous machinery of quality — and it shows up in the kind of work he publishes: quality improvement and patient safety studies alongside infertility clinical trials.

His research question of long standing is the uterus itself. Uterine fibroids are the most common pelvic tumor in women and a frequent cause of heavy bleeding, impaired implantation and pregnancy loss, and Rein has worked on their pathogenesis — the chromosomal abnormalities that arise inside fibroid tissue and the role progesterone plays in driving their growth. Those mechanisms are why some fibroids shrink after menopause, why some grow on hormonal stimulation, and why a patient planning IVF may be advised to have specific fibroids addressed first. He treats abnormal uterine bleeding, fibroids, female and male infertility and menopause.

He is a Duke University medical graduate who trained at Brigham and Women’s Hospital in both obstetrics and gynecology residency and reproductive endocrinology and infertility fellowship, and he has practiced for more than three decades. He holds an associate professorship at Harvard Medical School. His clinic is at 102-104 Endicott Street in Danvers, with a North Shore phone line, making him the member of this group whom Essex County patients can see without crossing into Boston — a scheduling advantage during a monitored cycle. Danvers is also where his Salem Hospital career was based. No board certification statement appears on the profile used for this page; his training record is documented instead.

Clinical Expertise

• Uterine fibroids in a fertility patient: deciding which fibroids matter for implantation and bleeding, and whether to treat surgically, hormonally or leave alone before IVF
• Abnormal uterine bleeding: structured evaluation of cause — polyps, fibroids, ovulatory dysfunction, endometrial pathology — rather than symptomatic hormonal suppression alone
• IVF, IUI and ovulation induction for female and male factor infertility, with cycle monitoring available on the North Shore
• Menopause and perimenopause care, including symptom management for patients whose fertility treatment is finished or declined
• Clinical trials in infertility: an active investigator record in trial participation, which is how patients access study protocols
• Safety and systems review: two decades of hospital-level oversight of surgical and obstetric quality behind his operative recommendations

Why Choose Dr. Rein

A physician who ran a hospital’s medical staff. Few fertility specialists have held chief medical officer responsibility for nineteen years, and it is the sort of background that makes complication risk and referral timing treated as concrete decisions rather than abstractions.

Fibroids are his published subject, not an occasional case. Pathogenesis research on fibroid genetics and progesterone response informs how conservative or aggressive he is about removing them before pregnancy.

Danvers, with a local phone line. 102-104 Endicott Street, reachable on the 978 area code, for patients from Salem north and east who would otherwise drive into Boston for every monitoring visit.

Three decades of practice, Duke medical school and Brigham and Women’s training, Harvard Medical School associate professor.

Professional Affiliations

American College of Obstetricians and Gynecologists; American Society for Reproductive Medicine; Society for Reproductive Endocrinology and Infertility; Massachusetts Medical Society. Associate Professor of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School. Former Chief Medical Officer and Senior Vice President, Salem Hospital (2004-2023); former Chair, Obstetrics and Gynecology (1997-2006). Practice site: 102-104 Endicott Street, Suite 304, Danvers.

Suitable For

• Patients with fibroids being told that a myomectomy, an IVF cycle, or both are on the table
• Heavy or irregular bleeding interfering with conception attempts or with quality of life in perimenopause
• North Shore residents who need frequent monitoring appointments close to home
• Couples wanting trial participation for infertility treatment
• Women navigating menopause after, or instead of, fertility treatment