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2026 Top #31 Fertility Clinic in the US 🏆 TOP 50

Source: Newsweek 2026 America's Best Fertility Clinics

Center for Reproductive Medicine and Robotic Surgery (GoFertility)

US United States
· St. Louis
CAP·College of American Pathologists Laboratory Accreditation ↗
Embryology laboratory accredited by the Reproductive Laboratory Program of the College of American Pathologists (CAP)
CLIA·Clinical Laboratory Improvement Amendments ↗
CLIA-certified clinical laboratory ensuring diagnostic and embryology testing quality
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Trusted hospital backed by real patient reviews
4.6
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Center for Reproductive Medicine and Robotic Surgery (GoFertility)
Center for Reproductive Medicine and Robotic Surgery (GoFertility) 2
Center for Reproductive Medicine and Robotic Surgery (GoFertility) 3

About

About Center for Reproductive Medicine and Robotic Surgery

GoFertility — officially the Center for Reproductive Medicine and Robotic Surgery (CRMRS) — is a nationally recognized IVF facility located in Creve Coeur, Missouri, about a 15-minute drive from St. Louis Lambert International Airport. The center was founded in 2011 by Dr. Saji Jacob, MD, FACOG, HCLD (ABB), one of only a handful of dual board-certified infertility specialists in the United States who holds both OB/GYN board certification and a high-complexity clinical laboratory director credential.

According to CDC 2022 ART data, the center reported 64 ART cycles; because most cycles are embryo banking cycles, CDC did not publish age-specific live birth rates (data suppressed). The center publishes its own pregnancy rate per embryo transfer — 76% in 2015, 81% in 2017 and 88% in 2019 — but those are clinic-reported figures on a per-transfer basis. With the center’s CDC 2022 age brackets suppressed, this page carries no national per-transfer benchmark to compare them against, and no CDC outcome rows of its own. Newsweek placed the center in its top-50 America’s Best Fertility Clinics list in 2023, 2024 and 2025; our source records no rank for any of those years, and the clinic’s own banner claims a top-50 spot “for 4 years in a row” without naming a fourth year. The clinic states it is one of only two Missouri fertility centers on that list.

Accreditations & Awards

  • Newsweek Top 50 IVF Center: named to the top-50 list in 2023, 2024 and 2025. Our source records no numeric rank for those years and no 2026 placement; the “4 years in a row” figure is the clinic’s own unranked banner claim
  • Dual board-certified leadership: Dr. Saji Jacob holds ABOG (Obstetrics & Gynecology) and ABB (High Complexity Clinical Laboratory Director) certifications, with trained embryologist credentials (Source: GoFertility website)
  • CDC 2022 reporting and clinic-published figures: 64 ART cycles in the CDC 2022 extract, with age-specific live birth rates suppressed because most cycles were embryo banking; the per-transfer pregnancy rates quoted on this page (76%, 81%, 88% for 2015-2019) are the center’s own website figures (Source: CDC NASS 2022; GoFertility website)
  • CAP-accredited embryology laboratory: the lab holds accreditation from the College of American Pathologists (CAP) and meets CLIA clinical laboratory standards
  • National robotic surgery proctor: Dr. Jacob is a certified robotic surgeon and national proctor who trains physicians across the U.S. in robotic gynecological surgery

Why Choose GoFertility (CRMRS)

  • One-on-one care with the physician: Dr. Jacob sees every patient at every appointment, ensuring highly personalized care — “You are not just a number to us.”
  • Clinical and laboratory expertise in one physician: as both a clinician and a trained embryologist, Dr. Jacob understands infertility from both the clinical and laboratory perspectives.
  • Clinic-reported outcomes: 88% pregnancy rate per embryo transfer in 2019 (76% in 2015, 81% in 2017), published on the center’s own website; the clinic’s CDC 2022 age-bracket live birth rates were suppressed, so there is no like-for-like national comparison on this page.
  • Robotic microsurgery specialty: a certified robotic surgeon with more than 1,000 complex robotic surgeries completed, specializing in stage IV endometriosis, myomectomy, and tubal reanastomosis.
  • Comprehensive fertility services: from basic fertility assessment to IVF/ICSI, PGT-A, donor egg, surrogacy support, egg freezing, and male infertility treatment.

IVF & Fertility Services

  • IVF (In Vitro Fertilization): conventional IVF and ICSI with blastocyst culture using complex tri-gas incubators that precisely control pH, CO₂, and O₂ levels.
  • PGT-A (Preimplantation Genetic Testing for Aneuploidy): chromosome screening to select euploid embryos and improve implantation success.
  • Egg Freezing & Fertility Preservation: for medical indications (e.g., before cancer treatment) or elective deferral of childbearing.
  • Donor Egg Program: actively recruiting young donors (compensation up to $30,000) for patients needing donor oocytes.
  • Surrogacy Program: medical support for gestational carrier arrangements.
  • Male Infertility Treatment: ICSI, PESA (percutaneous epididymal sperm aspiration), and TESA (testicular sperm aspiration).
  • IUI (Intrauterine Insemination): ovulation induction combined with IUI.
  • Embryo Banking / Split Cycle IVF: multiple retrieval cycles to accumulate embryos before transfer, designed for patients with low ovarian reserve.
  • Robotic Minimally Invasive Surgery: robotic-assisted endometriosis excision, myomectomy, and tubal microsurgical reanastomosis.
  • Gynecological Services: annual well-woman exams, hormone replacement therapy, and menopause management.

Fees & Packages

GoFertility accepts most major insurance plans, including United Healthcare and Cigna. A financial counselor helps patients understand insurance coverage and self-pay options. Specific fees vary by treatment plan and insurance coverage; patients are encouraged to discuss costs with the finance team before treatment. Online payment is available. The clinic does not publish fixed package prices on its website.

Patient Journey

  1. Initial consultation: schedule via online booking or phone; new patients typically receive an appointment within one week.
  2. Fertility assessment: comprehensive workup including hormone panel, AMH, transvaginal ultrasound, and semen analysis — completed within 14 days, with Dr. Jacob performing ultrasounds personally.
  3. Personalized treatment plan: the physician develops an individualized protocol and the financial counselor reviews coverage and self-pay options.
  4. Cycle treatment: ovarian stimulation → egg retrieval → IVF/ICSI fertilization → embryo culture → PGT testing (if applicable) → embryo transfer (fresh or frozen).
  5. Pregnancy confirmation and follow-up: blood β-hCG testing about 10-14 days after transfer, with continued support after confirmation.
  6. Patient portal: manage appointments, view medical records, and check lab results through the Prognocis patient portal.
  • Egg/sperm donation: legal in Missouri with a written agreement; donors relinquish parental rights.
  • Surrogacy: commercial surrogacy agreements are restricted under Missouri law — consult an attorney for current rules.
  • PGT-A/PGT-M: no special legal restrictions; standard medical informed consent and CLIA laboratory standards apply.
  • LGBTQ+ family building: Missouri offers limited legal protections for LGBTQ+ family-building rights; professional legal advice is recommended.
  • Embryo legal status: Missouri law does not clearly define embryo status; disposition is governed by reproductive agreements.

Location

  • Address: 844 N New Ballas Ct Ste 300, Creve Coeur, MO 63141, USA
  • Phone: +1 314-473-1285

Key Advantages

IVF Treatment
ICSI
PGT-A Genetic Screening
Egg Freezing
Donor Egg Program

Location

844 N New Ballas Ct Ste 300, Creve Coeur, MO 63141, USA

Facilities

Appointment Required
Wheelchair Accessible
Telehealth Available

Medical Team

Patient Reviews

4.6
79 reviews
5star
65%
4star
20%
3star
8%
2star
4%
1star
3%
S
Sarah Thoroughman
2 weeks ago

Dr. Jacob and his team made our dreams come true! The communication from the start to finish kept us comfortable and informed. We are so blessed and grateful for this team. Highly recommend!

K
Kristen Spencer
3 weeks ago

Dr . j and all of the staff are just amazing. Ashley makes everything simple and easy. We loved our experience, we can’t wait til we go back for our next baby. They were very lgbt friendly as well. We would recommend a million times! We’re so thankful to have our little girl. Shes so perfect

I
ItsMsRogers
2 months ago

The staff at this facility were very rude to me. Usually, medical offices have some kind of website or link they send you to get registration done. So when I asked them, they just kept repeating “there’s no link, there’s no website.” I’m a very antagonistic and condescending way. When I asked for help finding insurance they accept, nobody wanted to give me any companies. They just kept telling me (in a sarcastic way) how to sign up for it still not telling me who they accepted. So I kindly told them that it was unnecessary to speak to me that way and to not speak to me as if I’m dumb. When I finally got in contact with Dr Jacob, he wasn’t as rude, but wasn’t any better in my opinion. My visits with him were very rushed. He seemed to care more about me coming in to get my blood drawn like I’m a lab rat than helping me come up with a solution. He said the surgery I would need would cost $40K and that’s with insurance. I had surgery with another doctor and with insurance it was only $800 with insurance and $12K without. Yeah, Dr jacob doesn’t actually care he’s only money hungry. He also said I had two gigantic cyst on both of my ovaries. Which was a lie. Before I had surgery, my new doctor told me I only had 1 cyst and the other was perfectly healthy. Dr Jacob also told me I would never be able to have children and the surgery which was a lie because now I have a BEAUTIFUL 6 month old baby girl. I’m so glad I stopped seeing him.

L
Laura Obermoeller
6 months ago

I started my journey a little over four years ago at The Center for Reproductive Medicine and Robotic Surgery (CRMRS) with Dr. Jacobs, and I truly can’t say enough good things about my experience. From the very first appointment, you could tell that Dr. Jacobs is a doctor who genuinely cares about his patients. He always put my health and what was best for me first, never rushed appointments, and took the time to answer every single question. I felt supported, informed, and cared for throughout the entire journey. I was fortunate enough to get pregnant on the first round of IVF, and I am beyond grateful every single day for my little girl. I truly credit Dr. Jacobs and his team for making that possible. The entire staff was incredibly kind, but Ashley, his receptionist, deserves special recognition. She was absolutely amazing — always available to answer questions, help with medications, and guide us through the financial side of things in the most cost-efficient way possible. She went above and beyond to make a very overwhelming process feel manageable. The whole process from the beginning is an emotional and stressful journey, but the compassion, support, and dedication from Dr. Jacobs and his team made all the difference. I will always be grateful for the care I received and highly recommend CRMRS to anyone considering fertility treatment.

T
Tía Renee
1 year ago

I don’t want to say Dr Jacobs is the best…… But he ain’t nobody to play with… (meaning he’s the best) after 15 years of dealing with endometriosis dealing with bad Drs, Dr Jacob helped the Most High perform a miracle!!! When I say I love…...

L
Lashon Jones
1 year ago

Made me feel real uncomfortable. Basically saying just because I was an abused my fault. Every test he talked to me about I told him I’ve already done just a waste of $200. It’s very hard to keep going to doctors for them to take outta…...

B
Brittany Corn
1 year ago

He’s been a wonderful experience with him so far We couldn’t ask for a better doctor. We started with a different clinic, but we couldn’t ask for a better doctor with Dr. Jacobs . He’s the best and the business. I definitely recommend if…...

C
Christine
1 year ago

From the moment I entered Dr. Jacob’s office, I felt reassured that I was in capable hands. The first step was surgery to get rid of cysts, fibroids, scar tissue, and a fallopian tube. My husband and I appreciated Dr. Jacob for being so transparent and let us know that IVF would be our best bet to starting a family and to try immediately after surgery because the endometriosis will grow back in a matter of 6 months. We did not take Dr. Jacob’s advice right away and thus had to undergo a second surgery. We knew that after this second surgery it was go time and so thus our IVF journey began. Miraculously, on our first attempt, we were blessed with a healthy embryo. Now, as we celebrate our second trimester, we can hardly contain our excitement to meet our little one. We are incredibly grateful to Dr. Jacob for his dedication and support throughout our IVF process. He was straightforward and addressed all our concerns with patience, and his expertise ensured both surgeries went smoothly. I also want to give a special shout-out to Ashley, who uplifted our spirits during tough times, often without realizing how much we needed it. Her positivity, and willingness to answer my countless questions were invaluable. I really should get a shirt that says, "I have another question!" Lastly, I can't forget the wonderful Kaitlyn and Callie, who always brought joy and appreciated my IVF shirts that I would wear to the office. This journey was challenging so coming into the office with cute outfits was always so fun! I looked forward to their calls reminding me of appointments and other important updates. They were also fantastic at teaching us how to administer the medications. We truly couldn’t have navigated this without the entire team, who have now become like family to us. As a first-time IVF patient, stepping into this process felt like a leap of faith, and we are deeply thankful to Dr. Jacob, Ashley, Kaitlyn, and Callie. You are all truly AMAZING!

A
Alexandra Theisen
1 year ago

My husband and I are extremely grateful for the care we received from Dr. Jacob and the staff at CRMRS. We had previously seen a separate fertility specialist who had not completed a thorough workup. Once we transferred care to Dr. Jacob, due to his due diligence he found the reason behind our infertility issues (stage 4 endometriosis) and treated appropriately. Throughout our fertility journey we had multiple episodes where we had to call after hours and we always received prompt and efficient care, even late in the night. CRMRS provided us with an appropriate amount of hope but also realistic expectations based on our personal situation, which is exactly what excellent medical care should provide.

S
S G
2 years ago

Everyone at CRMRS is absolutely amazing. Dr. Jacob and Ashley are incredibly passionate about giving families hope and guidance through their entire fertility journey. Knowing I had such an amazing team leading me along made the high parts that much better and the low parts bearable. No one will go to bat for you more than this team!! I first went to Dr. Jacob with a referral from my OB to help treat my endometriosis. Dr. Jacob was able to remove a lot of endometriosis and diagnose me with Stage 4. My end goal was to have a baby and he and Ashley went through all the steps, meds, outcome percentages, everything. I felt very informed through the entire process. Dr. Jacob ended up doing two robotic surgeries and I went through two rounds of IVF and got pregnant! After years of doctors telling me it couldn’t happen, Dr. Jacob gave me hope that it still could. Thank you thank you thank you for my sweet baby angel!🩷🌹

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