Pacific Fertility Center

About Pacific Fertility Center

Pacific Fertility Center has been treating infertility in San Francisco since 1986, and on the most recent federal reporting published for it, it beat the national frozen-embryo benchmark in every age band where SART publishes one. SART 2023 final reporting (ClinicPKID 2075) shows live birth rates per transfer of frozen, PGT-A tested blastocysts at 51.6% under 35, 57.3% at 35-37, 51.6% at 38-40, 39.7% at 41-42, and 47.7% over 42 — the first four sit above the national frozen-transfer average for the same age group, and SART publishes no national figure for the over-42 group, so that last one goes unranked. The practice dates to 1986; its About page anchors the current center to 1999, when the present San Francisco organization took shape, and the clinic counts more than 13,000 babies welcomed across that history.

The main office sits at 55 Francisco Street in Rincon Square, a short walk from the Embarcadero transit hub, with a second location in Greenbrae serving Marin County and the North Bay. Pacific Fertility is part of The Prelude Network, a national reproductive medicine group, while keeping local physician leadership — Medical Director Isabelle Ryan, MD, who joined the center in 1999, oversees the clinical team and the egg bank. The embryology laboratory is in-house and CAP-accredited, and Pacific Fertility Egg Bank is described by the clinic as Northern California’s first frozen donor-egg program and the largest independent egg bank in the region.

Accreditations & Awards

• SART member clinic — cycle outcomes reported to the CDC through SART under a single Pacific Fertility Center registration (ClinicPKID 2075); 2023 final data is publicly verifiable, though SART does not break results out by the San Francisco versus Marin campus
• CAP-accredited embryology laboratory under CLIA-certified operation; the clinic also advertises an “IVF Lab Perfect Score Certification”
• Newsweek America’s Best Fertility Clinics — listed in the 2024 ranking and No. 46 nationally in 2026
• Fertility Equity Achievement Award — received in 2026 for inclusive-care commitments
• Castle Connolly Top Doctors — multiple physicians on staff, including recognition spanning 2010-2026 for Medical Director Isabelle Ryan, MD and 2017-2025 for Liyun Li, MD
• The Prelude Network member — shared protocols and laboratory standards across a national reproductive medicine network

Why Choose Pacific Fertility Center

• Outperformance across every age band, on the hardest metric. The 2023 SART numbers above are live births per transfer of genetically tested frozen blastocysts — the cycle path most Bay Area clinics now use — and PFC clears the national average in each band with a published comparator, including 41-42-year-olds at 39.7% against 29.3% nationally.
• Its own egg bank. Pacific Fertility Egg Bank lets the same physicians who run your cycle select, screen, and vitrify donor eggs in-house; the clinic pitches immediate donor availability and lower cost than fresh donation cycles.
• Monitoring that fits a workday. Early-morning, evening, and weekend appointments are standard practice for nurses, physicians, and the lab — a real consideration during stimulation, when scans land every two to three days.
• Serious LGBTQ+ depth. Brent Monseur, MD, who sees patients in San Francisco, founded Stanford Medicine’s Q+ LGBTQ+ Family Building clinic and chaired the American Society for Reproductive Medicine’s LGBTQ+ Special Interest Group.
• Mandarin-language care. Liyun Li, MD built PFC’s China Patient Program in 2014 and sees patients in spoken and written Mandarin; the clinic maintains a dedicated Chinese-language information page.
• Volume. The center reported 1,813 ART cycles in 2023, roughly double the ~932-cycle national per-clinic average — embryology teams at this scale see every lab problem twice.

IVF & Fertility Services

• In Vitro Fertilization (IVF) with ICSI, blastocyst culture, and frozen or fresh embryo transfer
• Egg freezing and fertility preservation, the anchor service of Pacific Fertility Egg Bank alongside donor-egg cycles
• Genetic testing: PGT-A (comprehensive chromosome screening) on embryos during IVF; the physicians’ profiles also reference carrier screening
• IUI and ovulation induction for simpler infertility presentations
• Donor egg and gestational surrogacy programs under a dedicated Third-Party Parenting service led by the medical director
• Male infertility treatment
• LGBTQ+ family building for same-sex couples, trans and nonbinary patients, and single parents by choice
• Reproductive surgery: laparoscopic and hysteroscopic procedures offered by the surgical members of the physician team
• International patient program with remote consultation, scheduling support, and Mandarin services
• Counseling and emotional-health support integrated with treatment teams

Fees & Packages

There is no published price list. The clinic’s FAQ references IVF cycles starting at about $11,930, and its financing page points patients to a financial coordination team for cycle-specific quotes rather than posting package rates. PFC works with patients’ medical insurance plans where coverage applies, self-pay pathways are standard, and a BUNDL fertility payment package is offered as an option. Expect medication costs, anesthesia, PGT biopsy and testing fees, and embryo storage to be quoted separately — ask the billing team for a written all-in estimate before starting stimulation.

Patient Journey

1. Consultation — in person at San Francisco or Marin, or remotely for international and out-of-state patients; fertility history and goals reviewed with a physician or nurse practitioner
2. Testing — ovarian reserve and hormone workup, semen analysis, imaging, and any genetic carrier screening indicated
3. Treatment plan — physician-built path calibrated to age, diagnosis, and budget; financial coordinator reviews insurance and payment options in parallel
4. Stimulation and monitoring — roughly 8-12 days of injectables with serial ultrasounds and bloodwork, available at early-morning, evening, and weekend hours
5. Retrieval and fertilization — transvaginal egg retrieval under sedation; ICSI or conventional insemination in the CAP-accredited in-house lab, with embryos cultured to blastocyst
6. PGT-A and cryopreservation — embryos biopsied and frozen pending screening results, which is why the clinic’s SART numbers above are frozen-transfer numbers
7. Transfer and confirmation — single frozen embryo transfer, blood pregnancy test about 10-14 days later, and monitoring continued through roughly 8-10 weeks

Local Legal Framework

California is among the most permissive ART states in the U.S., and Pacific Fertility’s service lineup — egg bank, surrogacy program, PGT — is built on that framework:

• Surrogacy: gestational carrier agreements are enforceable under Family Code Sections 7960-7962, with commercial arrangements recognized and pre-birth orders routinely available naming intended parents
• Egg and sperm donation: California does not prohibit clinical donation, and it is carried out on written informed consent. One correction worth stating plainly, because you will see the citation quoted around California fertility: Health and Safety Code Section 125355 governs compensation where eggs are collected for research, not clinical egg donation, so it is not the legal basis for a donor program. That a donor is not a legal parent of a child conceived from the donation runs through Family Code Section 7613 and, where the parties want it settled in advance, a court parentage order
• PGT: no state-level restriction on PGT-A or PGT-M beyond standard consent
• LGBTQ+ access: the Uniform Parentage Act and domestic partnership law (Family Code Sections 297-297.5) secure parentage for same-sex and unmarried intended parents; California bans conversion-adjacent refusals of fertility services
• Embryo status: embryos are special property, not legal persons; disposition is governed by the consent agreements signed at creation

Location

• Address: 55 Francisco St #500, San Francisco, CA 94133 (Marin office: 599 Sir Francis Drake Blvd #102, Greenbrae, CA 94904)
• Phone: +1 888-834-3095 / (415) 834-3000